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Lapatinib plus paclitaxel versus paclitaxel alone in the second-line treatment of HER2-amplified advanced gastric cancer in Asian populations: TyTAN--a randomized, phase III study.
  • T. Satoh, R. Xu, +16 authors Y. Bang
  • Medicine
  • Journal of clinical oncology : official journal…
  • 1 July 2014
TLDR
Lapatinib plus paclitaxel demonstrated activity in the second-line treatment of patients with HER2 FISH-positive IHC3+ advanced gastric cancer but did not significantly improve OS in the intent-to-treat population. Expand
Preoperative platelet lymphocyte ratio (PLR) is superior to neutrophil lymphocyte ratio (NLR) as a predictive factor in patients with esophageal squamous cell carcinoma
TLDR
This study demonstrated a better discrimination for the PLR in terms of hazard ratio(HR) than the NLR, indicating that PLR was superior to NLR as a predictive factor in patients with ESCC. Expand
Low preoperative lymphocyte to monocyte ratio predicts poor cancer-specific survival in patients with esophageal squamous cell carcinoma
TLDR
It is concluded that 2.93 may be the optimum cut-off point for LMR in predicting survival in ESCC patients and LMR is still a predictive factor for long-term survival in patients with ESCC. Expand
Significance of the prognostic nutritional index in patients with esophageal squamous cell carcinoma
TLDR
PNI is a predictive factor for long-term survival in ESCC and the survival rate of ESCC can be discriminated between three groups, ie, PNI <42, 42–52, and >52. Expand
Clinical Significance of Preoperative Neutrophil Lymphocyte Ratio versus Platelet Lymphocyte Ratio in Patients with Small Cell Carcinoma of the Esophagus
TLDR
The results of the present study conclude that PLR is superior to NLR as a predictive factor in patients with SCCE. Expand
Cisplatin plus gemcitabine versus paclitaxel plus gemcitabine as first-line therapy for metastatic triple-negative breast cancer (CBCSG006): a randomised, open-label, multicentre, phase 3 trial.
TLDR
Cisplatin plus gem citabine was both non-inferior to and superior to paclitaxel plus gemcitabine as first-line therapy for patients with metastatic triple-negative breast cancer in China. Expand
Combination of neutrophil lymphocyte ratio and platelet lymphocyte ratio is a useful predictor of postoperative survival in patients with esophageal squamous cell carcinoma
TLDR
The CNP is considered a useful predictor of postoperative survival in patients with esophageal squamous cell carcinoma and is superior to NLR or PLR as a predictive factor in Patients with ESCC. Expand
Comparison of complications of peripherally inserted central catheters with ultrasound guidance or conventional methods in cancer patients.
TLDR
Compared with CPICC, UPICC could improve the rate of successful insertion, reduce catheter related complications and increase comfort of the involved arm, thus deserving to be further investigated in randomized clinical studies. Expand
A nomogram to predict prognostic values of various inflammatory biomarkers in patients with esophageal squamous cell carcinoma.
TLDR
The nomogram based on CSS could be used as an accurately prognostic prediction for patients with esophageal squamous cell carcinoma, and GPS, PLR and LMR were potential prognostic biomarkers in patients with ESCC. Expand
Prognostic significance of neutrophil-to- lymphocyte ratio in esophageal cancer: a meta-analysis
TLDR
High NLR is associated with poor prognosis in patients with EC and may be a significant predictive biomarker in patientsWith EC, and pooled results demonstrated that high NLR was associated withpoor OS and DFS. Expand
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