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In alcohol-naïve systems, ethanol (<100mM) exposure of calcium-gated BK channels perturbs physiology and behavior. Brief (several minutes) ethanol exposure usually leads to increased BK current, which results from ethanol interaction with a pocket mapped to the BK channel-forming slo1 protein cytosolic tail domain. The importance of this region in(More)
OBJECTIVE To investigate the influence of Fasudil, a Rho inhibitor on the number and functions of the late endothelial progenitor cells in peripheral blood of chronic obstructive pulmonary diseases (COPD) patients with pulmonary artery hypertension. BACKGROUND It is not clear yet, whether Rho Kinase Inhibitor Fasudil can reduced pulmonary artery pressure(More)
  • Xu, Zhang, +8 authors Thomas Dd Differential
  • 2012
REFERENCES 1. Franks NP. General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal. 4. Raines DE. Anesthetic and nonanesthetic halogenated volatile compounds have dissimilar activities on nicotinic acetylcholine receptor desensitization kinetics. 5. Peoples RW, Weight FF. Cutoff in potency implicates alcohol inhibition of(More)
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