Jette Mistry

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Plasmodium knowlesi is an intracellular malaria parasite whose natural vertebrate host is Macaca fascicularis (the 'kra' monkey); however, it is now increasingly recognized as a significant cause of human malaria, particularly in southeast Asia. Plasmodium knowlesi was the first malaria parasite species in which antigenic variation was demonstrated, and it(More)
Using a variety of alpha-hydroxy hydroxamic acid derivatives, the size and shape of the S1' pocket for the CD23 processing metalloprotease has been explored. It has been demonstrated that a P1' 2-naphthylmethyl group occupies most of the available space and gives excellent selectivity against fibroblast collagenase (matrix metalloproteinase-1, MMP-1) and(More)
A phage DNA transfection assay is described that permits the measurement of frequencies of recombinant DNA molecules. This method was used to investigate the time course of action of the phage-specified generalized recombination system, the Red system, during lytic infection. Two observations of interest have emerged from this study: 1. There is a distinct(More)
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