Jesualdo Cherri

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Recent studies have demonstrated that skeletal muscle cells are resistant to prolonged periods of ischaemia, but damage is observed after reperfusion. Periods of time longer than three hours of normothermal ischaemia in skeletal muscle lead to irreversible lesions. In the present study muscle metabolism during ischaemia and reperfusion was studied. After(More)
BACKGROUND Oxygen free radicals are considered to be important components involved in the physiopathological tissue alterations observed during ischemia and reperfusion. The objective of the present study was to investigate oxidative stress based on indicators of oxygen free radical activity and on the changes in behavior of the lipoprotein membrane(More)
BACKGROUND Ischemia-reperfusion injury is believed to be a major cause of transferred skin flap failure. Cigarette smoking is known to be associated with endogenous antioxidant depletion, hypercoagulability, and cutaneous vasoconstriction. This investigation was carried out to study possible effects of pentoxyfilline or heparin on rat skin reperfusion(More)
BACKGROUND To establish the correlation between quantitative analysis based on B-mode ultrasound images of vulnerable carotid plaque and histological examination of the surgically removed plaque, on the basis of a videodensitometric digital texture characterization. METHODS Twenty-five patients (18 males, mean age 67 +/- 6.9 years) admitted for carotid(More)
BACKGROUND The role of mitochondrial lesions in the pathogenesis of irreversible cellular ischemia is controversial. The inability to restore mitochondrial function is correlated with the inability to reverse cell damage in various tissues. The objective of the present study was to compare parameters associated with oxidative phosphorylation and the inner(More)
This experimental investigation was carried out to study the endothelium-dependent ischemia-reperfusion injury upon the release of nitric oxide (NO) in the canine femoral artery. The tested experimental model was the inferior canine hindlimb ischemia induced by infrarenal abdominal aortic clamping followed by reperfusion. The research protocol was(More)
BACKGROUND Several vascular complications are known to occur in association with the acquired immunodeficiency syndrome (AIDS) and recent publications have called attention to the development of pseudoaneurysms of large arteries in patients with AIDS. CASE REPORT We report on 2 patients with AIDS aged 23 and 31 years with pseudoaneurysms of the abdominal(More)
The effect of digitoxin on isolated segments of lateral branches of the human saphenous vein perfused in vitro with constant volumes is reported. Digitoxin, depending on concentraion, effected rise in perfusion pressure and intensification of reaction to norepinephrine. Some venous segments showed spontaneous activity. The tests were supported by(More)
Background: Several vascular complications are known to occur in association with the acquired immunodeficiency syndrome (AIDS) and recent publications have called attention to the development of pseudoaneurysms of large arteries in patients with AIDS. Case report: We report on 2 patients with AIDS aged 23 and 31 years with pseudoaneurysms of the abdominal(More)