Jessica Opoku-Anane

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In humans, all alpha beta CD8+ T cells express NKG2D, but in mouse, it is only expressed by activated and memory CD8+ T cells. We purified human naive CD8+ T cells to show that NKG2D serves as a costimulatory receptor for TCR induced Ca2+ mobilization and proliferation. The resulting effector cells are skewed toward a type 1 phenotype and produce high(More)
Laparoscopy may prove feasible to address surgical needs in limited-resource settings. However, no aggregate data exist regarding the role of laparoscopy in low- and middle-income countries (LMICs). This study was designed to describe the issues facing laparoscopy in LMICs and to aggregate reported solutions. A search was conducted using Medline, African(More)
Women who cannot negotiate condom use with their partners, often due to socioeconomic factors and sexual abuse, have no means of preventing themselves from acquiring the human immunodeficiency virus (HIV). There is a need to develop HIV-preventive methods initiated and controlled by women. Microbicides and other pre-exposure prophylaxis may help fill that(More)
BACKGROUND AND OBJECTIVES To assess the feasibility and safety of minimally invasive hysterectomy for uteri >1 kg. METHODS Clinical and surgical characteristics were collected for patients in an academic tertiary care hospital. Included were patients who underwent minimally invasive hysterectomy by 1 of 3 fellowship-trained gynecologists from January 1,(More)
We read with interest the article by Ito et al,1 in which the authors reported the largest case series of hysterectomies performed for extremely enlarged uteri via a minimally invasive approach, either laparoscopic or robot-assisted. With the only exception being the way the specimen was removed after hysterectomy, the surgical technique described by the(More)
INTRODUCTION With the growing controversy surrounding power morcellation (PM), other approaches must be examined so that women may still benefit from minimally invasive gynecologic surgeries. In this study we sought to compare power morcellation to manual morcellation through mini-laparotomy or vaginally. MATERIALS AND METHODS Retrospective cohort study(More)
OBJECTIVE To assess perioperative outcomes and identify predictors of complications for minimally invasive surgery (MIS) myomectomy in a cohort of women with large and numerous myomata. DESIGN Case-control study (Canadian Task Force classification II-2). SETTING Academic tertiary care medical center. PATIENTS Women undergoing MIS myomectomy performed(More)
Purpose: Minor gynecologic surgery is the cornerstone of gynecologic evaluation and intervention in countries with a well-established medical infrastructure. Surgical training and exposure to minor procedures are not available in low and middle-income countries due to the complex challenges of patient delay and lack of access to healthcare, physician(More)
INTRODUCTION Operative morbidity of laparoscopic myomectomy largely relates to the potential for intraoperative blood loss. We sought to determine if blood loss varies according to the menstrual cycle. MATERIAL AND METHODS A retrospective review of 268 women who underwent a laparoscopic myomectomy from 2007 to 2012. Patients were categorized into five(More)
STUDY OBJECTIVE To assess whether a robotic simulation curriculum for novice surgeons can improve performance of a suturing task in a live porcine model. DESIGN Randomized controlled trial (Canadian Task Force classification I). SETTING Academic medical center. PATIENTS Thirty-five medical students without robotic surgical experience. INTERVENTIONS(More)
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