Jessica Opoku-Anane

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In humans, all alpha beta CD8+ T cells express NKG2D, but in mouse, it is only expressed by activated and memory CD8+ T cells. We purified human naive CD8+ T cells to show that NKG2D serves as a costimulatory receptor for TCR induced Ca2+ mobilization and proliferation. The resulting effector cells are skewed toward a type 1 phenotype and produce high(More)
Laparoscopy may prove feasible to address surgical needs in limited-resource settings. However, no aggregate data exist regarding the role of laparoscopy in low- and middle-income countries (LMICs). This study was designed to describe the issues facing laparoscopy in LMICs and to aggregate reported solutions. A search was conducted using Medline, African(More)
Women who cannot negotiate condom use with their partners, often due to socioeconomic factors and sexual abuse, have no means of preventing themselves from acquiring the human immunodeficiency virus (HIV). There is a need to develop HIV-preventive methods initiated and controlled by women. Microbicides and other pre-exposure prophylaxis may help fill that(More)
(2014). Minor gynecologic surgery: A review of the training experience and skill building opportunities for providers in low and middle income countries. Abstract Purpose: Minor gynecologic surgery is the cornerstone of gynecologic evaluation and intervention in countries with a well-established medical infrastructure. Surgical training and exposure to(More)
BACKGROUND AND OBJECTIVES To assess the feasibility and safety of minimally invasive hysterectomy for uteri >1 kg. METHODS Clinical and surgical characteristics were collected for patients in an academic tertiary care hospital. Included were patients who underwent minimally invasive hysterectomy by 1 of 3 fellowship-trained gynecologists from January 1,(More)
INTRODUCTION With the growing controversy surrounding power morcellation (PM), other approaches must be examined so that women may still benefit from minimally invasive gynecologic surgeries. In this study we sought to compare power morcellation to manual morcellation through mini-laparotomy or vaginally. MATERIALS AND METHODS Retrospective cohort study(More)
STUDY OBJECTIVE To assess whether a robotic simulation curriculum for novice surgeons can improve performance of a suturing task in a live porcine model. DESIGN Randomized controlled trial (Canadian Task Force classification I). SETTING Academic medical center. PATIENTS Thirty-five medical students without robotic surgical experience. INTERVENTIONS(More)
OBJECTIVE To assess perioperative outcomes and identify predictors of complications for minimally invasive surgery (MIS) myomectomy in a cohort of women with large and numerous myomata. DESIGN Case-control study (Canadian Task Force classification II-2). SETTING Academic tertiary care medical center. PATIENTS Women undergoing MIS myomectomy performed(More)
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