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SbcC-SbcD and ExoI process convergent forks to complete chromosome replication
Significance SbcC-SbcD and ExoI belong to a class of highly conserved nucleases that are critical to genome stability, but whose cellular function remains poorly understood. Human homologs of theseExpand
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Limited Capacity or Involvement of Excision Repair, Double-Strand Breaks, or Translesion Synthesis for Psoralen Cross-Link Repair in Escherichia coli
DNA interstrand cross-links are complex lesions that covalently bind complementary strands of DNA and whose mechanism of repair remains poorly understood. In Escherichia coli, several gene productsExpand
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The Limitations of DNA Interstrand Cross-link Repair in Escherichia coli
DNA interstrand cross-links are complex lesions that covalently bind complementary strands of DNA and whose mechanism of repair remains poorly understood. In Escherichia coli, several gene productsExpand
Rolling Circle Mutagenesis of GST-mCherry to Understand Mutation, Gene Expression, and Regulation†
Undergraduates are often familiar with textbook examples of human mutations that affect coding regions and the subsequent disorders, but they may struggle with understanding the implications ofExpand