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Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment.
A medium-sensitivity assay for C-reactive protein (CRP) was compared with a high-sensitivity, enhanced immunoturbidimetric assay in 803 angiographically studied patients. Different absolute CRPExpand
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Lipoprotein-associated phospholipase A2 independently predicts the angiographic diagnosis of coronary artery disease and coronary death.
BACKGROUND Whereas C-reactive protein (CRP) is a nonspecific marker of coronary artery disease (CAD) and cardiovascular (CV) events, Lp-PLA2 may be a nonvariable inflammatory biomarker. We evaluatedExpand
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Multiple less common genetic variants explain the association of the cholesteryl ester transfer protein gene with coronary artery disease.
OBJECTIVES The objective of this study was to identify associations of the cholesteryl ester transfer protein (CETP) gene with coronary artery disease (CAD) with tagging (t) single nucleotideExpand
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Roles of Nrf2 in drug and chemical toxicity
Abstract The transcription factor Nrf2 regulates the basal and inducible expression of numerous cell defence genes, and thus protects mammalian cells against the deleterious effects of chemical andExpand
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Transcriptional characterisation of the Exaiptasia pallida pedal disc
BackgroundBiological adhesion (bioadhesion), enables organisms to attach to surfaces as well as to a range of other targets. Bioadhesion evolved numerous times independently and is ubiquitousExpand
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Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.
OBJECTIVE The aim of this study is to discover common variants in 6 lipid metabolic genes and construct and validate a genetic risk score (GRS) based on the joint effects of genetic variants inExpand
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High‐Resolution Characterization of Linkage Disequilibrium Structure and Selection of Tagging Single Nucleotide Polymorphisms: Application to the Cholesteryl Ester Transfer Protein Gene
Full characterization of intragenic variation may improve candidate gene associations. This study selected tagging (t) single nucleotide polymorphisms (SNPs) to comprehensively represent geneticExpand
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Common Variants in 6 Lipid-Related Genes Discovered by High-Resolution DNA Melting Analysis and Their Association with Plasma Lipids.
BACKGROUND: Total cholesterol was among the earliest identified risk factors for coronary heart disease (CHD). We sought to identify genetic variants in six genes associated with lipid metabolism andExpand
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The Role of Hydrogen Bonding in Peptoid-Based Marine Antifouling Coatings
The benefits of incorporating amphiphilic properties into antifouling and fouling-release coatings are well-established. The use of sequence-defined peptides and peptoids in these coatings allowsExpand
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