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Spermatid head elongation with normal nuclear shaping requires ADP-ribosyltransferase PARP11 (ARTD11) in mice.

• Mirella L. Meyer-Ficca, Motomasa Ihara, Jessica J. Bader, N. Adrian Leu, Sascha Beneke, Ralph G. Meyer
• Biology of reproduction
• 2015

Sperm are highly differentiated cells characterized by their species-specific nuclear shapes and extremely condensed chromatin. Abnormal head shapes represent a form of teratozoospermia that can… (More)

Alteration of poly(ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation

• Mirella L. Meyer-Ficca, Julia D. Lonchar, Motomasa Ihara, Jessica J. Bader, Ralph G. Meyer
• Chromosoma
• 2013

The mammalian sperm nucleus is characterized by unique properties that are important for fertilization. Sperm DNA retains only small numbers of histones in distinct positions, and the majority of the… (More)

Cell death and autophagy under oxidative stress: roles of poly(ADP-Ribose) polymerases and Ca(2+).

• Philippe Wyrsch, Christian Blenn, Jessica J. Bader, Felix R. Althaus
• Molecular and cellular biology
• 2012

On the cellular level, oxidative stress may cause various responses, including autophagy and cell death. All of these outcomes involve disturbed Ca(2+) signaling. Here we show that the nuclear… (More)

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