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  • Jérôme Fagart, Jessica Huyet, G. Pinon, Marina Rochel, Claudine Mayer, Marie-Edith Rafestin-Oblin
  • Biology, Medicine
  • Nature Structural &Molecular Biology
  • 2005 (First Publication: 1 June 2005)
  • The S810L mutation within the human mineralocorticoid receptor (MR S810L) induces severe hypertension and switches progesterone from antagonist to agonist. Here we report the crystal structures ofExpand
  • Mohammad Ozeir, Jessica Huyet, +15 authors Pierre Nioche
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2019 (First Publication: 3 June 2019)
  • The reversible adenine phosphoribosyltransferase enzyme (APRT) is essential for purine homeostasis in prokaryotes and eukaryotes. In humans, APRT (hAPRT) is the only enzyme known to produce AMP inExpand