Jessica H Savage

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BACKGROUND Egg allergy is very common, affecting 1% to 2% of children. It is generally thought that the majority of children with egg allergy develop tolerance in early childhood; however, this has not been examined in a large cohort with egg allergy. OBJECTIVE The purpose of the study was to estimate the proportion of children with egg allergy who(More)
Objectives: To assess the effectiveness of regular singing exercises in reducing symptoms of snoring and sleep apnoea. Methods: A prospective single blinded randomised controlled trial was conducted in the otolaryngology department of a UK teaching hospital (Exeter). 127 adult patients with a history of simple snoring or sleep apnoea were recruited. 93(More)
BACKGROUND Endocrine-disrupting compounds (EDCs) have immune-modulating effects. We were interested in determining their association with allergic sensitization. OBJECTIVE We sought to determine the association between EDCs and allergic sensitization and whether this relationship depends on the antimicrobial properties of the EDCs, sex, or both. METHODS(More)
BACKGROUND Soy allergy is very common, affecting approximately 0.4% of children. It is generally thought that the majority of children with soy allergy develop tolerance in early childhood; however, this has not been examined in a large cohort with soy allergy. OBJECTIVE We sought to describe the natural history of soy allergy and identify predictors of(More)
BACKGROUND Alterations in the intestinal microbiome are prospectively associated with the development of asthma; less is known regarding the role of microbiome alterations in food allergy development. METHODS Intestinal microbiome samples were collected at age 3-6 months in children participating in the follow-up phase of an interventional trial of(More)
BACKGROUND Transfusion-related characteristics have been hypothesized to cause allergic transfusion reactions (ATRs) but they have not been thoroughly studied. The primary objective of this study is to evaluate the associations of infusion rate, infusion volume, ABO mismatching, component age, and pretransfusion medication with the incidence and severity of(More)
BACKGROUND A recent study of subjects with peanut allergy treated with omalizumab generated some results that were concordant with a study of subjects with cat allergy treated with omalizumab. However, there were differences that provided additional insight into the nature of the cellular responses in allergic subjects. OBJECTIVE We sought to determine(More)
Among the rarest of the visceral aneurysms, gastroduodenal artery (GDA) aneurysms often present with spontaneous rupture and are associated with a high mortality rate. Their aetiology is poorly understood. This report describes a case of haemorrhagic shock due to sudden GDA aneurysm rupture in a patient with a significant autoimmune history.
BACKGROUND The prevalence of food allergy is thought to be increasing, but data from the United States have not been systematically synthesized. OBJECTIVE To summarize the data on prevalence of food allergy in the US pediatric population and to estimate the effects of time, race/ethnicity, and method of assessing food allergy on the estimated prevalence.(More)