Jessica E Treisman

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wingless inhibits morphogenetic furrow movement in the Drosophila eye disc.

Differentiation of the Drosophila eye imaginal disc is an asynchronous, repetitive process which proceeds across the disc from posterior to anterior. Its propagation correlates with the expression of… (More)

A Drosophila TNF-receptor-associated factor (TRAF) binds the Ste20 kinase Misshapen and activates Jun kinase

Hongzhi Liu, Yi-Chi Su, Elena Becker, Jessica E Treisman, Edward Y Skolnik
Current Biology
1999

Two families of protein kinases that are closely related to Ste20 in their kinase domain have been identified - the p21-activated protein kinase (Pak) and SPS1 families [1-3]. In contrast to Pak… (More)

The Drosophila Tuberous Sclerosis Complex Gene Homologs Restrict Cell Growth and Cell Proliferation

Nicolas Tapon, Naoto Ito, Barry J. Dickson, Jessica E Treisman, Iswar K Hariharan
Cell
2001

The inherited human disease tuberous sclerosis, characterized by hamartomatous tumors, results from mutations in either TSC1 or TSC2. We have characterized mutations in the Drosophila Tsc1 and… (More)

Synergy between the hunchback and bicoid morphogens is required for anterior patterning in Drosophila

Marcia Simpson-Brose, Jessica E Treisman, Claude Desplan
Cell
1994

Anterior patterning of the Drosophila embryo is specified by the localized expression of the gap genes, which is controlled by the gradient of the maternal morphogen bicoid (bcd). Another maternal… (More)

A single amino acid can determine the DNA binding specificity of homeodomain proteins

Jessica E Treisman, Pierre Gönczy, Malini Vashishtha, Eva Harris, Claude Desplan
Cell
1989

Many Drosophila developmental genes contain a DNA binding domain encoded by the homeobox. This homeodomain contains a region distantly homologous to the helix-turn-helix motif present in several… (More)

The Conserved microRNA MiR-8 Tunes Atrophin Levels to Prevent Neurodegeneration in Drosophila

Janina S. Karres, Valérie Hilgers, Inés Carrera, Jessica E Treisman, Stephen Michael Cohen
Cell
2007

microRNAs (miRNAs) bind to specific messenger RNA targets to posttranscriptionally modulate their expression. Understanding the regulatory relationships between miRNAs and targets remains a major… (More)

act up Controls Actin Polymerization to Alter Cell Shape and Restrict Hedgehog Signaling in the Drosophila Eye Disc

Aude Benlali, Irena Draškovič, Dennis J. Hazelett, Jessica E Treisman
Cell
2000

Cells in the morphogenetic furrow of the Drosophila eye disc undergo a striking shape change immediately prior to their neuronal differentiation. We have isolated mutations in a novel gene, act up… (More)

Cell-Autonomous and -Nonautonomous Functions of LAR in R7 Photoreceptor Axon Targeting

Corinne Maurel-Zaffran, Takashi Suzuki, Gabriele Gahmon, Jessica E Treisman, Barry J. Dickson
Neuron
2001

During Drosophila visual system development, photoreceptors R7 and R8 project axons to targets in distinct layers of the optic lobe. We show here that the LAR receptor tyrosine phosphatase is… (More)

Lightoid and Claret: a rab GTPase and its putative guanine nucleotide exchange factor in biogenesis of Drosophila eye pigment granules.

Jinping Ma, Heide Plesken, Jessica E Treisman, Irit Edelman-Novemsky, Mindong Ren
Proceedings of the National Academy of Sciences…
2004

To elucidate the biogenetic pathways for the generation of lysosome-related organelles, we have chosen to study the Drosophila eye pigment granules because they are lysosome-related and the fruit fly… (More)

pannier acts upstream of wingless to direct dorsal eye disc development in Drosophila.

Corinne Maurel-Zaffran, Jessica E Treisman
Development
2000

The dorsoventral midline of the Drosophila eye disc is a source of signals that stimulate growth of the eye disc, define the point at which differentiation initiates, and direct ommatidial rotation… (More)

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