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Journals and Conferences
Drugs with antidopaminergic properties and those capable of stimulating serotonin release can be responsible for hyperthermia syndromes such as neuroleptic malignant syndrome and serotonin syndrome. Dopamine and serotonin are important neurotransmitters in temperature regulation and it is likely that these reactions result from drug-induced changes in… (More)
OBJECTIVE To report the frequency and severity of optical coherence tomography (OCT) retinal thickness measurement errors and to describe parameters that predict these errors. DESIGN Observational case series. PARTICIPANTS Two hundred consecutive patients undergoing OCT imaging. METHODS One eye (primary) from each of 200 consecutive patients… (More)
This study assessed the accuracy of oscillotonometric blood pressure measurement in critically ill patients during transfer. Direct intra-arterial pressure measurements were taken in 44 transported patients as a 'gold standard' and compared with readings from four portable automatic oscillotonometers--the Dinamap 8100, Lifestat 100, Propaq 102 and Takeda… (More)
Plasma paracetamol concentrations were measured after oral administration of three pharmaceutical preparations to four healthy volunteers. The formulations were Paramax (paracetamol with metoclopramide), Solpadeine (paracetamol with codeine and caffeine) and Panadol (paracetamol alone). After Solpadeine, concentrations at 15 min were significantly higher… (More)
Critically ill patients transferred between hospitals are often inadequately monitored in transit, with outcome adversely affected. In 22 such patients, we compared direct and palpated measurements of systolic pressure, oscilloscopic and aneroid manometric measurements of mean pressure, ECG and palpated measurements of heart-rate and clinical and oximetric… (More)
Patients in a state of persistent vegetation or 'cognitive death' are an emotional drain on their family, and a financial drain on a society with limited resources. In this article, society's responsibility towards these patients and the moral and ethical issues involved in the withdrawal of fluid and nutrition are discussed.
Tracheal intubation is a skill that should be considered supplementary to other aspects of airway management which are of vital importance in resuscitation. Doctors involved in resuscitation should develop and retain such skills, and be aware of potential dangers.