Jessica A. Kado

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Mouse myeloid leukemia M1 cells were induced to differentiate in vitro into macrophages and granulocytes by various inducers, including dexamethasone. Prostaglandin F2 alpha inhibited the inductions by dexamethasone of phagocytic and lysozyme activities in M1 cells. Prostaglandin F2 alpha stimulated the production of differentiation-inhibiting activity(More)
It is known that human keratinocytes (KCs) express Toll-like receptors (TLRs). However, published reports conflict regarding TLR expression in cutaneous T-cell lymphoma patient's KCs. To define the pattern of expression and detect any differences of TLRs 1-9 and p65 expression in epidermal KCs, tumor infiltrate, and endothelial cell types using(More)
Toll-like receptors (TLRs) are known to be expressed in the skin. Antigenic stimulation of TLRs in the skin has been implicated in several inflammatory dermatologic diseases including psoriasis, syphilis, atopic dermatitis, and cutaneous T-cell lymphoma. However, the expression of TLRs in cutaneous sarcoidosis has not yet been defined. Expression of TLRs(More)
BACKGROUND Topical bexarotene 1% gel is currently FDA-approved for early stage (IA and IB) persistent or refractory cutaneous T-cell lymphoma (CTCL). No uniformly effective therapy exists for follicular mucinosis, although several treatments are routinely used. There are no known reports of topical bexarotene being used in the treatment of idiopathic(More)
Recently, the uses of intralesional cryosurgery (ILC) have been rapidly expanding in the field of dermatology and oncology. Thus far, ILC has been effectively used to treat keloids, hidradenitis suppurativa (HS), basal cell carcinomas (BCCs), and cutaneous metastases. These conditions can be difficult to treat so it is significant to have an alternative,(More)
We report the case of a 62-year-old Caucasian female with an 11-year history of an asymptomatic and unchanging plaque on her left shoulder. Physical examination revealed a 2.5cm round atrophic plaque with slight central nodularity and telangiectasias overlying a light-brown pigment network. The lesion was clinically most consistent with a scar from a prior(More)
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