Jesse Z. Fang

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Optical monitoring of activity provides new kinds of information about brain function. Two examples are discussed in this article. First, the spike activity of many individual neurons in small ganglia can be determined. Second, the spatiotemporal characteristics of coherent activity in the brain can be directly measured. This article discusses both general(More)
The descending pain inhibitory system (DPIS) associated with acupuncture analgesia (AA), caused by low frequency stimulation of an acupuncture point, was identified by the results of lesion and stimulation procedures previously determined to differentiate the afferent and efferent paths in rats. The DPIS starts in the posterior arcuate nucleus and descends(More)
The effects of 5-hydroxytryptamine (5-HT) microinjection into the nucleus raphe magnus (NRM) and the nucleus raphe dorsalis (NRD) on tonic pain were studied using the monosodium urate (MSU) tonic pain model in the rat. For the NRM, 5-HT microinjection produced significant analgesic effects, which were antagonized by systemic naloxone administration and also(More)
L-glutamic acid, bicuculline (a GABA receptor antagonist), lidocaine and GABA were injected into entopeduncular and habenular nuclei respectively in rats. Pain threshold was measured by the latency of avoidance response (tail-flick) elicited by radiant heat exposure before and after intracerebral injection. Microinjection of different concentration of(More)
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