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OBJECTIVE To determine whether regional cerebral blood flow (rCBF) is abnormal in any cerebral structure of women with fibromyalgia (FM), following a report that rCBF is reduced in the thalami and heads of caudate nuclei in FM. METHODS Seventeen women with FM and 22 healthy women had a resting single-photon-emission computed tomography (SPECT) brain scan(More)
PURPOSE To evaluate the ability and safety of a hydrophilic acrylic intraocular lens (IOL) as a drug-delivery system for commercially available gatifloxacin and moxifloxacin. SETTING David J. Apple, MD, Laboratories for Ophthalmic Research, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah,(More)
OBJECTIVE To analyze and compare the geometry of the anterior segment of rabbit and human eyes, with relevance for the evaluation of intraocular lenses, and to review rabbit models used in our laboratory for the evaluation of different ophthalmic devices and solutions. PROCEDURES Fifteen rabbit and 15 human eyes (10 phakic and 5 pseudophakic/group)(More)
PURPOSE To evaluate and compare the incidence of capsular bag opacification, particularly interlenticular opacification (ILO), in rabbit eyes implanted with a dual-optic silicone intraocular lens (IOL) or piggyback lenses. SETTING John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. METHODS Ten dual-optic study IOLs (Synchrony), 10(More)
PURPOSE To verify the presence of the element silicon on hydrophilic acrylic intraocular lenses (IOLs) explanted because of calcification. DESIGN Interventional case series with clinicopathological correlation. METHODS Twenty explanted IOLs with surface deposits (MemoryLens), and 20 with deposits mostly within their optic substance (SC60B-OUV and(More)
BACKGROUND Gatifloxacin and moxifloxacin ophthalmic solutions are frequently prescribed for antimicrobial prophylaxis following cataract and corneal refractive surgeries, although the use of topical antibiotics is likely to interfere with wound healing in the immediate postoperative period. A potential factor that may influence rates of wound healing or(More)
A 55-year-old man had uneventful phacoemulsification with implantation of a 3-piece silicone intraocular lens (IOL). Postoperative medications included antibiotic-steroid drops and ointments. Eight months postoperatively, the patient started having recurrent episodes of anterior chamber inflammatory reaction. Suspicion that lens instability was causing the(More)
BACKGROUND Regeneration/proliferation of lens material within the capsular bag still is the most frequent complication after cataract surgery. We aimed to evaluate the effects of hydrodissection with low doses of antimitotics on the overall regeneration/proliferation of lens material in rabbit eyes, using a model allowing the lens material to be confined to(More)
PURPOSE To evaluate meridional differences in angle-to-angle (A-A) and sulcus-to-sulcus (S-S) dimensions in human eyes using very high frequency ultrasound (VHF US) and anterior segment optical coherence tomography (AS-OCT). SETTING John A. Moran Eye Center, University of Utah, USA; Berlin Eye Research Institute, Germany; Quattroelle Centri(More)