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A simple and advantageous protocol for the oxidation of alcohols with O-iodoxybenzoic acid (IBX).
TLDR
An efficient, user-friendly procedure for the oxidation of alcohols using IBX is described, which gives excellent yields of the corresponding carbonyl compounds.
Synthesis of (±)-DiosponginA: A Hetero-Diels-Alder and C-Glycosylation Approach
The racemic natural product diospongin A has been prepared using a short and stereoselective sequence. Key steps include a hetero-Diels-Alder reaction and an anchimeric assistance-controlled
Synthesis of the Commercial Antidepressant Moclobemide.
An experiment for the undergraduate organic chemistry laboratory is described in which students synthesize the commercial antidepressant drug moclobemide, marketed under the trade name Manerix. This
Synthesis of the bicyclic core of the nucleoside antibiotic octosyl acid A.
TLDR
The bicyclic core of octosyl acid A has been prepared using a diastereoselective acetylide addition and 6-endo selenoetherification as key steps and difficulties encountered in the conversion of a phenyl group to a carboxylic acid will be discussed.
A Stereoselective Approach to the Core Structure of the Polyoxin and Nikkomycin Antibiotics
TLDR
A stereoselective synthesis of the core structure of the polyoxin and nikkomycin antibiotics is described and should be amenable to the large-scale preparation of numerous polyoxin analogs.
Synthesis of (.+‐.)‐Diospongin A: A Hetero‐Diels—Alder and C‐Glycosylation Approach.
The stereoselective synthesis of title compound (VII) is based on the Diels—Alder reaction catalyzed by ACC and a final anchimeric assistance-controlled C-glycosylation of the acetate (V).
SYNTHESIS OF FUROPYRANYL PYRIMIDINE NATURAL PRODUCTS. A REVIEW
INTRODUCTION ...................................................................................................................... 109 I . OCTOSYL ACID