Jesse A. Davidson

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INTRODUCTION Limited evidence suggests that serum alkaline phosphatase activity may decrease after cardiac surgery in adults and children. The importance of this finding is not known. Recent studies, however, have identified a potential role for alkaline phosphatase as modulator of inflammation in multiple settings, including during adult cardiopulmonary(More)
RATIONALE Decreased alkaline phosphatase activity after infant cardiac surgery is associated with increased post-operative cardiovascular support requirements. In adults undergoing coronary artery bypass grafting, alkaline phosphatase infusion may reduce inflammation. Mechanisms underlying these effects have not been explored but may include decreased(More)
The title compound, [HP(CH3)3][IrCl4{(H3C)3P}2], consists of a tri-methyl-phospho-nium cation and a tetra-chlorido-bis-(tri-methyl-phosphane)iridate(III) anion. The anion has an octa-hedral arrangement of ligands, with the tri-methyl-phosphane groups occupying trans positions. The Ir(III) atom sits on an inversion center with one P(CH3)3 ligand and two(More)
BACKGROUND The utility of procalcitonin (PCT) and C-reactive protein (CRP) as infectious biomarkers following infant cardiothoracic surgery is not well defined. METHODS We designed a prospective cohort study to evaluate PCT and CRP after infant cardiothoracic surgery. PCT and CRP were drawn preoperatively and 24/72 h postoperation or daily in delayed(More)
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