Jesmin Akter

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Identifying the pathways involved in the apoptotic cell death that is associated with polymyxin-induced nephrotoxicity is crucial for the development of strategies to ameliorate this dose-limiting side effect and for the development of novel safer polymyxins. The primary aim of this study was to identify the major pathways which lead to polymyxin-induced(More)
Polymyxin B and colistin were examined for their ability to inhibit the type II NADH-quinone oxidoreductases (NDH-2) of three species of Gram-negative bacteria. Polymyxin B and colistin inhibited the NDH-2 activity in preparations from all of the isolates in a concentration-dependent manner. The mechanism of NDH-2 inhibition by polymyxin B was investigated(More)
The dry antibiotic development pipeline coupled with the emergence of multidrug resistant Gram-negative 'superbugs' has driven the revival of the polymyxin lipopeptide antibiotics. Polymyxin resistance implies a total lack of antibiotics for the treatment of life-threatening infections. The lack of molecular imaging probes that possess native polymyxin-like(More)
The   ) ( exp    -expansion method is a promising method for finding exact traveling wave solutions to nonlinear evolution equations in physical sciences. In this article, we use the   ) ( exp    -expansion method to find the exact solutions for the nonlinear Zakharov-Kuznetsov-Benjamin-Bona-Mahony equation and the good Boussinesq equations. Many(More)
Australia is facing a major national medical challenge with the emergence of the Hendra virus (HeV) as a medically and economically important pathogen of humans and animals. Clinical symptoms of human HeV infection can include fever, hypotension, dizziness, encephalitis, respiratory haemorrhage and edema. The window of opportunity for successful patient(More)
The increasing social and economic implications caused by pathogenic bacteria means there is a constant striving to develop near antibacterial agents. The present study was carried out in vitro to determine antibacterial activity of Polyalthia longiflia (Debdaru) leaf extracts with hexane, methanol and chloroform against six tested pathogenic bacteria viz.(More)
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