Jesús Piñero

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CIGB-247 is a cancer therapeutic vaccine, based on recombinant modified human vascular endothelial growth factor (VEGF) as antigen, in combination with the adjuvant VSSP, a bacterially-derived adjuvant. The vaccine have demonstrated efficacy in several murine malignancy models. These studies supported the rationale for a phase I clinical trial where safety,(More)
Monte Carlo simulation and theoretical results on some aspects of structure and thermodynamics of polyelectrolyte solutions at room temperature are presented. The solution is mimicked by an infinitely long cylindrical polyion surrounded by point counterions. Both standard histogram method and Widom’s particle insertion method are utilized in the simulations(More)
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