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Two nested pharmacokinetic models are considered in this work. Several observations are taken on the same subject so they are correlated. The covariance function assumed is an exponential covariance function. Optimal exact designs are computed with different criteria , both for discriminating between models and estimating parameters. Compound criteria to(More)
The pathology of the Benign Paroxysmal Positional Vertigo (BPPV) is detected by a clinician through maneuvers consisting of a series of consecutive head turns that trigger the symptoms of vertigo in patient. A statistical model based on a new maneuver has been developed in order to calculate the volume of endolymph displaced after the maneuver. A(More)
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