Jesús Jiménez Barbero

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The microtubule binding affinities of a series of synthetic taxanes have been measured with the aims of dissecting individual group contributions and obtaining a rationale for the design of novel compounds with the ability to overcome drug resistance. As previously observed for epothilones, the positive and negative contributions of the different(More)
Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, 28040 Madrid, Spain Institute of Materia Medica, Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, P. R. China. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical(More)
15 N) mediante el etiquetado químico, tanto de los ligandos como de los receptores, con metales paramagnéticos (lantánidos). Estas metodologías se extienden al estudio de otros sis-temas biológicos y modelos químicos de reconocimiento molecular (p. péptidos antibióticos u otros) en colaboraciones que se mantienen con otros grupos del Departamento y del CIB,(More)
OBJECTIVE To know the characteristics of medical care at home done by the doctor and to what extent it is justified. DESIGN An observational, descriptive-prospective study. Form filled out by the doctor after completing the visit. SETTING Outpatients, 7 hospitals in area 17 of the Valencian Community. PATIENTS 188 different patients attended in(More)
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