Jesús González

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Voltage-gated ion channels regulate many physiological functions and are targets for a number of drugs. Patch-clamp electrophysiology is the standard method for measuring channel activity because it fulfils the requirements for voltage control, repetitive stimulation and high temporal resolution, but it is laborious and costly. Here we report an(More)
Efficient reef management strategies rely on detailed knowledge of biological exchange dynamics. At present, available connectivity information on Mexican Atlantic reefs is scarce, particularly concerning the Veracruz Reef System (VRS), which is located in the south-western Gulf of Mexico. This study used a hierarchically nested sampling design to evaluate(More)
Fluorescence resonance energy transfer (FRET) is a physical dipole– dipole coupling between the excited state of a donor fluorophore and an acceptor chromophore that causes relaxation of the donor to a non-fluorescent ground state, which excites fluorescence in the acceptor. Initially described by Förster (1948), FRET has been exten-In practical terms, the(More)
Pairs of membrane-associated molecules exhibiting fluorescence resonance energy transfer (FRET) provide a sensitive technique to measure changes in a cell's membrane potential. One of the FRET pair binds to one surface of the membrane and the other is a mobile ion that dissolves in the lipid bilayer. The voltage-related signal can be measured as a change in(More)
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