Jerzy Wydmański

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PURPOSE To study locoregional tumor control in postoperative radiotherapy (PRT) for head-and-neck cancer in relation to the position and duration of treatment gaps, duration of the interval surgery-radiotherapy, and to the other potentially prognostic variables. METHODS AND MATERIALS The retrospective study included 868 patients with cancer of the larynx,(More)
PURPOSE To present an interim analysis of the trial comparing two neoadjuvant therapies for unresectable rectal cancer. METHODS Patients with fixed cT3 or cT4 or locally recurrent rectal cancer without distant metastases were randomized to either 5 × 5 Gy and 3 courses of FOLFOX4 (schedule I) or 50.4 Gy delivered in 28 fractions given simultaneously with(More)
AIMS Evaluation of analgesic uptake, pain intensity, and quality-of-life changes after half-body irradiation of patients with bone metastases. MATERIAL AND METHODS Ninety-five patients (97 irradiations) were treated with single half-body irradiation fraction (3-8 Gy). Thirty-three patients had upper-half-body irradiation, 55 lower-half-body irradiation(More)
OBJECTIVE The aim of this study was to evaluate interfraction uncertainties using kilovoltage (kV) radiographs for patients with gastric cancer during chemoradiotherapy and to calculate the planning target volume (PTV) margins. METHODS 1284 measurements of set-up errors were analysed for treated patients. The measurements of craniocaudal (axis y),(More)
BACKGROUND Acanthosis nigricans (AN) develops sporadically or in association with obesity, insulin-resistance and dark pigmentary phenotype. Unusual clinical presentations of AN may be diagnostically vexing. OBJECTIVES The aim of the report is to present unusual clinical and dermoscopic pictures of hyper-keratotic, brownish lesions of the nipples(More)
PURPOSE The aim of this paper is to evaluate efficacy of radiotherapy for giant cell tumor of bone given either postoperatively or as sole treatment, and to assess prognostic factors for treatment outcome. METHODS AND MATERIALS The study includes 37 patients. In 9 cases, soft tissue involvement was noted. Nonradical operation followed by radiotherapy was(More)
Post-surgical radiation therapy is a routine procedure in the treatment of primary malignant brain tumors. Along with modest therapeutic effects conventional fractionated radiotherapy, in spite of any modifications, produces damage to non-malignant brain tissues lying within the treatment volume, the extent of which depends on radiation dose. Serial 1H-MRS(More)
Thyroid stimulating hormone (S-TSH) and thyroxine (S-T4) were measured in sera from 80 patients with breast cancer using radioimmunoassay. The patients had been irradiated after mastectomy 7.2 +/- 1.0 years earlier with 45 Gy in 3 to 4 weeks to parasternal, ipsilateral supraclavicular and axillary areas. Five patients (6%) had hypothyroidism with low S-T4(More)
BACKGROUND Improvements in local control are required when using preoperative chemoradiation for cT4 or advanced cT3 rectal cancer. There is therefore a need to explore more effective schedules. PATIENTS AND METHODS Patients with fixed cT3 or cT4 cancer were randomized either to 5 × 5 Gy and three cycles of FOLFOX4 (group A) or to 50.4 Gy in 28 fractions(More)
PURPOSE To inspect the potential diagnostic role of in vivo 1H MRS lipid methylene CH2 to methyl CH3 signal ratio in differentiation of recurrent brain tumor from radiation injury. METHODS Two patients--one with documented recurrence and the other without recurrence--were monitored by means of 1H MRS before and during two years after radiation therapy.(More)