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UDP-glucuronosyltransferases (UGTs) convert dietary constituents, drugs, and environmental mutagens to inactive hydrophilic glucuronides. Recent studies have shown that the expression of the UGT1 and UGT2 gene families is regulated in a tissue-specific fashion. Human small intestine represents a major site of resorption of dietary constituents and orally(More)
Greig cephalopolysyndactyly syndrome, characterized by craniofacial and limb anomalies (GCPS; MIM 175700), previously has been demonstrated to be associated with translocations as well as point mutations affecting one allele of the zinc finger gene GLI3. In addition to GCPS, Pallister-Hall syndrome (PHS; MIM 146510) and post-axial polydactyly type A (PAP-A;(More)
Topp, J. and L. Volkmann, On packing and covering numbers of graphs, Discrete Mathematics 96 (1991) 229-238. In this paper we present a characterization of connected graphs of order (k + 1)n with k-covering number n, a characterization of trees in which the k-packing and k-covering numbers are the same, and we prove that the smallest number of subgraphs(More)