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CONTEXT Two relatively unknown and recently described placental membrane hypoxic lesions (laminar necrosis and microscopic chorionic pseudocysts) have never been compared with time-honored, focal (infarction), and diffuse hypoxic lesions of placental parenchyma. OBJECTIVE To compare the effect on placental diagnosis of the above placental membrane hypoxic(More)
OBJECTIVE The purpose of this study was to evaluate placental lesions found in women with preeclampsia compared with normotensive control subjects and to determine whether the presence of these lesions are related to gestational age at delivery. STUDY DESIGN Placental disease of women with preeclampsia at 24 to 42 weeks of gestation was compared with the(More)
CONTEXT The thyroid gland is vulnerable to the carcinogenic effects of ionizing radiation, and there is a well-documented inverse correlation between thyroid cancer and age at exposure, particularly for ages less than 20 yr. One of the factors responsible for this phenomenon may be more rapid cell proliferation in children. OBJECTIVE The objective of this(More)
  • Jerzy Stanek
  • 2011
Placental membrane microscopic chorionic cysts (MCC) are associated with clinical conditions and placental features of in utero hypoxia. Those occurring in the cell islands, chorionic plate, placental septa, and maternal floor of the chorionic disc have been thought to have degenerative/liquefactive or secretory etiology and no clinical significance. To(More)
We report a case of fatal congenital cytomegalovirus (CMV) disease in a 695 gm, 29 weeks estimated gestational age premature infant. The newborn presented with hydrops fetalis, an unusual presentation of congenital CMV infection. In spite of ganciclovir therapy, the infant succumbed to his illness. Autopsy findings revealed the presence of widespread CMV(More)
OBJECTIVES To describe three cases of placental mesenchymal dysplasia (PMD) associated with abnormal karyotype and review the cases reported in the literature. METHODS The cases were retrieved from the files of three different institutions. A search of the English language literature was performed using Medline database. RESULTS Placental abnormalities(More)
CONTEXT In utero hypoxia is an important cause of perinatal morbidity and mortality and can be evaluated retrospectively to explain perinatal outcomes, to assess recurrence risk in subsequent pregnancies, and to investigate for medicolegal purposes by identification of many hypoxic placental lesions. Definitions of some placental hypoxic lesions have been(More)
Lobular capillary hemangiomas are common, benign, vascular soft-tissue tumors located in the head and neck during the childhood and early adulthood. Report of these lesions in the central nervous system has been anecdotal. The case of one patient treated for spinal cord compression secondary to a capillary hemangioma with elevated proliferation index is(More)
AIM To study the relation of retention of dead fetus resulting in its maceration and gestational age at delivery to placental diagnosis. METHODS Some 75 clinicoplacental phenotypes have been retrospectively analyzed in 520 consecutive stillbirths, 329 macerated and 191 nonmacerated, and at three gestational age interval cohorts (330 second trimester, 102(More)
This is a retrospective analysis of sensitivity and specificity of clustered placental basal plate multinucleate trophoblastic giant cells for various clinical conditions and placental lesions associated with fetal and placental hypoxia. Selected clinical and placental parameters of 375 consecutive cases of placentas with clusters of multinucleate(More)