Jerry A. Krishnan

Edward T Naureckas4
Min J Joo3
Gregory B Diette2
Shannon S Carson2
4Edward T Naureckas
3Min J Joo
2Gregory B Diette
2Shannon S Carson
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BACKGROUND Treatment of chronic diseases such as chronic obstructive pulmonary disease (COPD) is complicated by the presence of comorbidities. The objective of this analysis was to estimate the prevalence of comorbidity in COPD using nationally-representative data. METHODS This study draws from a multi-year analytic sample of 14,828 subjects aged 45+,(More)
Detecting abnormal health is an important issue for mobile health, especially for chronic diseases. We present a free-living health monitoring system based on simple standalone smart phones, which can accurately compute walking speed. This phone app can be used to validate status of the major chronic condition, Chronic Obstructive Pulmonary Disease (COPD),(More)
BACKGROUND Although older adults (> or =65 years) with asthma have higher rates of hospitalization and death from asthma than younger adults, the reasons for this are not known. OBJECTIVES To determine whether patterns of care were less favorable for older than younger adults with asthma and to assess whether patient characteristics such as symptom(More)
The Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN) represents an unprecedented collaboration across diverse healthcare institutions including private, county, and state hospitals and health systems, a consortium of Federally Qualified Health Centers, and two Department of Veterans Affairs hospitals. CAPriCORN builds on the strengths of(More)
BACKGROUND Because of concerns about the safety of long-acting β(2)-agonist (LABA) use in patients with asthma, withdrawal of the LABA is recommended by the US Food and Drug Administration once asthma is controlled by combination therapy with a LABA and inhaled corticosteroid (ICS). OBJECTIVE To perform a systematic review and meta-analysis assessing(More)
BACKGROUND The Patient Reported Outcomes Measurement Information System 43-item short form (PROMIS-43) and the five-level EQ-5D (EQ-5D-5L) are recently developed measures of health-related quality of life (HRQL) that have potentially broad application in evaluating treatments and capturing burden of respiratory-related diseases. The aims of this study were:(More)
  • Amit K Mahajan, Gregory B Diette, Umur Hatipoğlu, Andrew Bilderback, Alana Ridge, Vanessa Walker Harris +6 others
  • 2011
BACKGROUND High frequency chest wall oscillation (HFCWO) is used for airway mucus clearance. The objective of this study was to evaluate the use of HFCWO early in the treatment of adults hospitalized for acute asthma or chronic obstructive pulmonary disease (COPD). METHODS Randomized, multi-center, double-masked phase II clinical trial of active or sham(More)
At the core of the healthcare crisis is a fundamental lack of actionable data, needed to stratify individuals within populations, to predict which persons have which outcomes. A new health system with better health management will require better health measurement, to improve cost and quality. It is now possible to use new technologies to provide the rich(More)
BACKGROUND Objective measurement of airflow obstruction by spirometry is an essential part of the diagnosis of asthma or COPD. During exacerbations, the feasibility and utility of spirometry to confirm the diagnosis of asthma or chronic obstructive pulmonary disease (COPD) are unclear. Addressing these gaps in knowledge may help define the need for(More)
BACKGROUND Asthma represents a significant clinical and economic burden to the US healthcare system. Along with other clinical manifestations of the disease, elevated sputum and blood eosinophil levels are observed in patients experiencing asthma exacerbations. The aim of this study was to evaluate the association between blood eosinophil levels and asthma(More)