Jerry A. Krishnan

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BACKGROUND Treatment of chronic diseases such as chronic obstructive pulmonary disease (COPD) is complicated by the presence of comorbidities. The objective of this analysis was to estimate the prevalence of comorbidity in COPD using nationally-representative data. METHODS This study draws from a multi-year analytic sample of 14,828 subjects aged 45+,(More)
BACKGROUND Although older adults (> or =65 years) with asthma have higher rates of hospitalization and death from asthma than younger adults, the reasons for this are not known. OBJECTIVES To determine whether patterns of care were less favorable for older than younger adults with asthma and to assess whether patient characteristics such as symptom(More)
Detecting abnormal health is an important issue for mobile health, especially for chronic diseases. We present a free-living health monitoring system based on simple standalone smart phones, which can accurately compute walking speed. This phone app can be used to validate status of the major chronic condition, Chronic Obstructive Pulmonary Disease (COPD),(More)
BACKGROUND In the United States, morbidity from asthma disproportionately affects African Americans and women. Although inadequate care contributes to overall asthma morbidity, less is known about differences in asthma care by race and sex. SUBJECTS AND METHODS To examine the relationships of race and sex with asthma care, we analyzed responses to(More)
BACKGROUND Little evidence on the validity of simple and widely applicable tools to predict mortality in patients with chronic obstructive pulmonary disease (COPD) exists. OBJECTIVE To conduct a large international study to validate the ADO index that uses age, dyspnoea and FEV(1) to predict 3-year mortality and to update it in order to make prediction of(More)
BACKGROUND Because of concerns about the safety of long-acting β(2)-agonist (LABA) use in patients with asthma, withdrawal of the LABA is recommended by the US Food and Drug Administration once asthma is controlled by combination therapy with a LABA and inhaled corticosteroid (ICS). OBJECTIVE To perform a systematic review and meta-analysis assessing(More)
The Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN) represents an unprecedented collaboration across diverse healthcare institutions including private, county, and state hospitals and health systems, a consortium of Federally Qualified Health Centers, and two Department of Veterans Affairs hospitals. CAPriCORN builds on the strengths of(More)
The National Children's Study will address, among other illnesses, the environmental causes of both incident asthma and exacerbations of asthma in children. Seven of the Centers for Children's Environmental Health and Disease Prevention Research (Children's Centers), funded by the National Institute of Environmental Health Sciences and the U.S.(More)
BACKGROUND High frequency chest wall oscillation (HFCWO) is used for airway mucus clearance. The objective of this study was to evaluate the use of HFCWO early in the treatment of adults hospitalized for acute asthma or chronic obstructive pulmonary disease (COPD). METHODS Randomized, multi-center, double-masked phase II clinical trial of active or sham(More)