Jerry A. Krishnan

Learn More
STUDY OBJECTIVES To assess the consistency of caloric intake with American College of Chest Physicians (ACCP) recommendations for critically ill patients and to evaluate the relationship of caloric intake with clinical outcomes. DESIGN Prospective cohort study. SETTING Adult ICUs at two teaching hospitals. PARTICIPANTS Patients with an ICU length of(More)
RATIONALE The patterns and outcomes of noninvasive, positive-pressure ventilation (NIPPV) use in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease (COPD) nationwide are unknown. OBJECTIVES To determine the prevalence and trends of noninvasive ventilation for acute COPD. METHODS We used data from the Healthcare Cost(More)
CONTEXT Little is known about how depressive symptoms in mothers affects illness management in inner-city children with asthma. OBJECTIVE Our goal was to determine how maternal depressive symptoms influence child medication adherence, impact of the child's asthma on the mother, and maternal attitudes and beliefs. METHODS Baseline and 6-month surveys(More)
Weaning protocols can improve outcomes, but their efficacy may vary with patient and staff characteristics. In this prospective, controlled trial, we compared protocol-based weaning to usual, physician-directed weaning in a closed medical intensive care unit (ICU) with high physician staffing levels and structured, system-based rounds. Adult patients(More)
Use of a volume- and pressure-limited mechanical ventilation strategy improves clinical outcomes of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS). However, the extent to which tidal volumes and inspiratory airway pressures should be reduced to optimize clinical outcomes is a controversial topic. This article addresses(More)
BACKGROUND Airborne pollutants and indoor allergens increase asthma morbidity in inner-city children; therefore, reducing exposure, if feasible, should improve asthma morbidity. OBJECTIVE To conduct a randomized controlled trial of methods to reduce environmental pollutant and allergen exposure in the homes of asthmatic children living in the inner city.(More)
OBJECTIVE To determine whether caloric intake is associated with risk of nosocomial bloodstream infection in critically ill medical patients. DESIGN Prospective cohort study. SETTING Urban, academic medical intensive care unit. PATIENTS Patients were 138 adult patients who did not take food by mouth for > or =96 hrs after medical intensive care unit(More)
OBJECTIVE Pulmonary arterial hypertension related to scleroderma (PAH-Scl) is associated with high morbidity and mortality as well as poorer response to therapy and worse outcomes compared with the idiopathic form of PAH (IPAH). Scleroderma is an autoimmune disease that can affect left and right heart function directly through inflammation and fibrosis and(More)