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Clustering techniques have been used by many intelligent software agents in order to retrieve, lter, and categorize documents available on the World Wide Web. Clustering is also useful in extracting salient features of related web documents to automatically formulate queries and search for other similar documents on the Web. Traditional clustering(More)
The clearance and volume of distribution of five human proteins (recombinant CD4, CD4 immuno-globulin G, growth hormone, tissue-plasminogen activator, and relaxin) in humans and laboratory animals were analyzed as a function of body weight using allometric scaling techniques. These proteins cover a 16-fold range of molecular weight (6 to 98 kD), are(More)
We present WebACE, an agent for exploring and categorizing documents on the World Wide Web based on a user proole. The heart of the agent is an unsupervised cat-egorization of a set of documents, combined with a process for generating new queries that is used to search for new related documents and for ltering the resulting documents to extract the ones(More)
BACKGROUND Chronic ischemic heart disease may lead to ventricular dilation and congestive heart failure (ischemic cardiomyopathy [ICM]). The changes in cardiac myocyte shape associated with this dilation, however, are not known. METHODS AND RESULTS Left ventricular myocyte dimensions were assessed in cells isolated from explanted human hearts obtained(More)
We propose an agent for exploring and categorizing documents on the World Wide Web based on a user proole. The heart of the agent is an automatic categorization of a set of documents, combined with a process for generating new queries used to search for new related documents and lter-ing the resulting documents to extract the set of documents most closely(More)
BACKGROUND This study compared angiographically graded coronary blood flow with intracoronary Doppler flow velocity in patients during percutaneous transluminal coronary angioplasty (PTCA) for acute myocardial infarction. Different TIMI angiographic flow grades (flow grades based on results of the Thrombolysis in Myocardial Infarction trial) have been(More)
A patient with nodular sclerosing Hodgkin's disease had at least three episodes of lung involvement consisting of an infiltrate on one occasion and multiple cavitating nodules on the other two. The cytologic and histologic studies of the lung specimens disclosed the presence of Reed-Sternberg cells on each occasion without any evidence for infection. This(More)
BACKGROUND Transradial access is a recently developed alternative for diagnostic cardiac catheterization. Its effects on quality of life after the procedure, patient preference, and cost are unknown. METHODS AND RESULTS We performed a randomized single-center trial in which 99 patients underwent transfemoral and 101 underwent transradial diagnostic(More)
Three independent methods were evaluated in an effort to obtain reliable values for myocyte size in adult Sprague-Dawley rats. Cell volume was determined from isolated myocytes by a Coulter Channelyzer system. Cell volume was also determined from the product of length and cross-sectional area of isolated myocytes. Additionally, myocyte cross-sectional area(More)
The effect of chronic consumption of alcohol on the circadian variations of the plasma corticosterone was investigated in DBA/2J male mice. After 15 weeks of alcohol consumption (3.8%w/v for the first week and 7.5% for subsequent weeks) the alcohol groups exhibited a flattened circadian corticosterone curve, the level being intermediate between the peak and(More)