Jerome G. Jacobstein

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The present study was performed to evaluate scintigraphic imaging with technetium 99m-labeled glucoheptonate and serum enzyme levels of creatine phosphokinase isoenzyme (MB-CPK) in the early diagnosis of perioperative acute myocardial infarction associated with saphenous vein bypass graft operations. Myocardial imaging was done in 27 patients (50% of whom(More)
Bone scans were performed with Tc-99m stannous polyphosphate on four patients with thalassemia major. Three of the scans show generalized decrease in skeletal uptake of the radiopharmaceutical, associated with renal enlargement and markedly increased renal radioactivity. The skeletal findings are consistent with the known bone abnormalities in thalassemia(More)
An isolated-heart preparation has been adapted to permit rapid evaluation of, and imaging by, myocardial tracers. The rabbit heart provided a mass large enough for imaging and serial biopsies. Coronary arteries could be selectively ligated and provided landmarks for epicardial ST segment mapping. Uptake ratios between a tissue sample and normal myocardium(More)
Although patients with acute inferior myocardial infarction often manifest S-T segment depression in precordial electrocardiographic leads, the pathophysiologic abnormalities associated with this finding are poorly understood. To examine this problem, electrocardiographic findings on admission were compared with results of radionuclide cineangiography(More)
The clinical specificity and sensitivity of imaging with 99mTc was evaluated prospectively in 104 consecutive patients admitted to the hospital for diagnostic/surgical arthroscopy. Four distinct patterns of radionuclide activity were seen that correlated with observed arthroscopic findings. These patterns of activity were seen with degenerative joint(More)