Jeroen van der Aa

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We compared values of invasive blood pressure measured intra-arterially with those measured noninvasively with an automated oscillometric monitor. Twenty-eight patients undergoing cardiac surgical procedures under general anesthesia were studied and 552 determinations were made. The two methods of measuring blood pressure correlated within the expected(More)
BACKGROUND Multiparameter DNA flow cytometry using a one-laser bench-top flow cytometer has been restricted to three different colors. The two laser FACSCalibur has recently been introduced, allowing four-color analysis. Therefore, we optimized and extended our three-color method (Corver et al., 1994, Corver et al. 1996) to a four-color analysis of(More)
Disagreement as to the effect of glycopyrrolate and atropine sulphate at various dosages on heart rate has been reported in the literature. Of particular interest is the question of whether small doses of glycopyrrolate cause bradycardia. Three groups of subjects were studied. The QRS complexes of the electrocardiogram were continuously recorded on a(More)
In order to evaluate the possible physiologic significance of intra- and postoperative hypotension, we monitored arterial blood pressure and heart rate continuously for 36 hr starting the night before and ending the morning after operation in 34 gynecologic patients. The lowest pressures that occurred during physiologic sleep were compared with the lowest(More)
BACKGROUND AND OBJECTIVES To provide patients with better postoperative pain relief, the authors developed a prototype computer-controlled infusion pump capable of establishing a steady drug plasma concentration based on patient needs. METHODS A two-compartment pharmacokinetic model was used to compute the required infusion scheme. Using known(More)
The effects of positive end-expiratory pressure (PEEP) and lung compliance (CL) on delivered tidal volume (VTdel) and ventilator output were evaluated in the following anaesthesia machine/ventilator systems: Narkomed III with a Model AV-E ventilator (III/AV-E system) and an Ohmeda Modulus II with either a 7810 anaesthesia ventilator (II/7810 system) or a(More)
Perceiving temporal regularity in an auditory stimulus is considered one of the basic features of musicality. Here we examine whether zebra finches can detect regularity in an isochronous stimulus. Using a go/no go paradigm we show that zebra finches are able to distinguish between an isochronous and an irregular stimulus. However, when the tempo of the(More)
Mass spectrometry of respired gases puts a powerful analytic tool into the hand of the clinician. However, serious misinterpretations may result if the principle of operation and certain weaknesses of spectrometry are not appreciated. The potential pitfalls of clinical mass spectrometry are related to the need to have one unit serve many patients and to the(More)