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Many complex, real world phenomena are difficult to study directly using controlled experiments. Instead, the use of computer simulations has become commonplace as a cost effective alternative. However, regardless of Moorepsilas law, performing high fidelity simulations still requires a great investment of time and money. Surrogate modeling (metamodeling)(More)
Plasmodium vivax was maintained in experimentally infected Aotus nancymai. Positive monkeys were used as donors for culture material. After leucocyte removal with two different methods, including the classic CF11 method and a commercially available filter, parasites were grown under continuous shaking conditions in standard RPMI 1640, containing 20% human(More)
Three series of experiments were conducted to investigate the refractoriness of chickens to Trypanosoma (Schizotrypanum) cruzi. Firstly, 60 newly hatched chicks were inoculated with either bloodstream trypomastigotes or triatomine faecal stages of T. cruzi. The chicks were kept at low ambient temperatures, then killed at intervals and examined for infection(More)
In this paper, a modeling methodology to maximize the yield of a SRAM memory array is presented. The method is robust to process variations. Calibrated models for the distributions of performance parameters are used to predict the sensitivity of the design performance to variability. The calibration and the verification of the prediction are based on 130nm(More)