Jeroen Broeders

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Therapeutic drug monitoring (TDM) of tuberculosis (TB) drugs currently focuses on peak plasma concentrations, yet total exposure [area under the 24-h concentration-time curve (AUC₀₋₂₄)] is probably most relevant to the efficacy of these drugs. We therefore assessed population AUC₀₋₂₄ data for all four first-line TB drugs (rifampicin, isoniazid, pyrazinamide(More)
Solid-phase extraction (SPE) is an established sample-preparation technique for clean-up procedures of polycyclic aromatic hydrocarbons (PAHs). The suitability of monofluorinated polycyclic aromatic hydrocarbons (F-PAHs) as a novel set of internal standards, was tested for two widely used SPE sorbents, octyl-bonded silica and styrene-divinylbenzene(More)
Bridging the gap between state of the art consumer electronics and bio-analytical setups designed for lab environments, an embedded, miniaturised, stand-alone measurement device is developed. The presented impedance analyser incorporates most of the data communication features present in current-generation smartphones and is specifically optimised for(More)
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