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Following birth, when mammals are relatively immobile, significant development of the motor system facilitates weight bearing and locomotion. Prominent cholinergic C-terminals develop on somata and proximal dendrites of spinal motoneurons during this time period. It is hypothesized that these terminals are essential in regulating motoneuron excitability and(More)
The present simulations were designed to determine whether the current}voltage (I}<) relationship obtained during voltage clamp was su$cient to characterise the kinetics and distribution of dendritic Ca> channels in spinal motoneurones. Two models were constructed, one based on a fully reconstructed adult cat motoneurone (neuromorphic model) the second a(More)
  • Bruce C.V. Campbell, Michael D. Hill, Marta Rubiera, Bijoy K. Menon, Andrew Demchuk, Geoffrey A. Donnan +18 others
  • 2016
Table II-III – Patient and procedural characteristics for sensitivity analyses Table IV-V – Patient outcomes in the sensitivity analyses Tables VI-VIII – Patient outcomes for those treated with alteplase within 0-3 hours and 3-4.5 hours after stroke onset Table IX – Rates of mTICI at final angiogram and associated rates of independent outcome Figures I-II –(More)
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