Allan V Kalueff13
Siddharth Gaikwad13
Evan Kyzar8
Adam Michael Stewart8
13Allan V Kalueff
13Siddharth Gaikwad
8Evan Kyzar
8Adam Michael Stewart
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We tested the hypothesis that, given the consistency of tone-syllable alignment found in recent research, accuracy of tone perception is dependent on the accuracy of syllable perception. In two experiments, subjects either judged the number of syllables or identified the tones in nonsense sentences that were spectrally intact, low-pass filtered at 300 Hz or(More)
The marketing team of a new telecommunications company is usually tasked with producing forecasts for diverse stakeholders with different needs. Consequently, those outside marketing often do not realize the many reasons for developing forecasts , nor the marketing theory used and the challenges involved in doing so. Based on our three decades of experience(More)
Zebrafish (Danio rerio) are rapidly emerging as a useful animal model in neurobehavioral research. Mounting evidence shows the suitability of zebrafish to model various aspects of anxiety-related states. Here, we evaluate established and novel approaches to uncover the molecular substrates, genetic pathways and neural circuits of anxiety using adult(More)
Zebrafish (Danio rerio) are rapidly becoming an important model organism in neuroscience research, representing an excellent species to study complex social phenotypes. Zebrafish actively form shoals, which can be used to quantify their shoaling behaviors, highly sensitive to various experimental manipulations. Recent advances in video-tracking techniques(More)
Satellite systems are beginning to incorporate complex autonomous operations, which calls for rigorous reliability assurances. Human operators usually plan satellite maneuvers in detail, but autonomous operation will require software to make decisions using noisy sensor data and problem solutions with numerical inaccuracies. For such systems, formal(More)
Par-1 encodes a serine/threonine kinase that is involved in asymmetric segregation of cell fate determinants in Caenorhabditis elegans and Drosophila embryos. Recent biochemical studies indicate an association of PAR-1 with the Dishevelled protein and suggest a role in so-called canonical Wnt signaling (Nat. Cell Biol. 3 (2001) 628). Here we describe two(More)
Ketamine is a non-competitive glutamatergic antagonist used to induce sedation and analgesia. In sub-anesthetic doses, it induces hyperlocomotion, impairs memory and evokes stereotypic circling in rodents. Zebrafish (Danio rerio) emerged as a promising new animal model to screen the effects of psychotropic compounds. Here, we investigated the effects of(More)
Intra-session habituation to novelty reflects spatial working memory (related to exploration and cognition), and is observed in various species, including zebrafish (Danio rerio). With the growing understanding of complex zebrafish behaviors, the extent to which they habituate remains unclear. Here we perform a large-scale characterization of zebrafish(More)
Rodent self-grooming is an important, evolutionarily conserved behavior, highly sensitive to pharmacological and genetic manipulations. Mice with aberrant grooming phenotypes are currently used to model various human disorders. Therefore, it is critical to understand the biology of grooming behavior, and to assess its translational validity to humans. The(More)
Mescaline and phencyclidine (PCP) are potent hallucinogenic agents affecting human and animal behavior. As their psychotropic effects remain poorly understood, further research is necessary to characterize phenotypes they evoke in various animal models. Zebrafish (Danio rerio) are rapidly emerging as a new model organism for neuroscience research. Here, we(More)