• Publications
  • Influence
Isotope-edited FTIR reveals distinct aggregation and structural behaviors of unmodified and pyroglutamylated amyloid β peptides.
Amyloid β peptide (Aβ) is causatively associated with Alzheimer's disease (AD), and N-terminally truncated and pyroglutamylated Aβ peptides (AβpE) exert hypertoxic effect by an unknown mechanism.Expand
  • 12
  • PDF
Site-Specific Structural Changes in Unmodified and Pyroglutamylated Amyloid Beta Peptide by Isotope-Edited Ftir
Amyloid beta-peptide (Abeta) forms cytotoxic assemblies that contribute to Alzheimer's disease. Recent evidence indicates that prefibrillar aggregates and not the fibrillar deposits exert the mainExpand