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Detection of Biosynthetic Precursors, Discovery of Glycosylated Forms, and Homeostasis of Calcitonin in Human Cancer Cells.
The peptide hormone calcitonin is intimately connected with human cancer development and proliferation. Its biosynthesis is reasoned to proceed via glycine-, α-hydroxyglycine-, glycyllysine-, andExpand
Regulation Mechanisms of Peptide Hormones in Neuroendocrine Cancers
In the work described in this thesis, analytical methods for the detection and quantification of peptide hormones featuring on-line analyte concentration, postseparation tagging and HPLC-fluorescenceExpand