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  • Influence
Neural compensation in older people with brain β-amyloid deposition
Recruitment of extra neural resources may allow people to maintain normal cognition despite amyloid-β (Aβ) plaques. Previous fMRI studies have reported such hyperactivation, but it is unclear whetherExpand
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Effects of Beta-Amyloid on Resting State Functional Connectivity Within and Between Networks Reflect Known Patterns of Regional Vulnerability.
Beta-amyloid (Aβ) deposition is one of the hallmarks of Alzheimer's disease (AD). However, it is also present in some cognitively normal elderly adults and may represent a preclinical disease state.Expand
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Dynamic changes in parietal activation during encoding: Implications for human learning and memory
The ventral posterior parietal cortex (vPPC) monitors successful memory retrieval, yet its role during learning remains unclear. Indeed, increased vPPC activation during stimulus encoding is oftenExpand
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Influence of young adult cognitive ability and additional education on later-life cognition
  • W. Kremen, A. Beck, +13 authors C. Franz
  • Psychology, Medicine
  • Proceedings of the National Academy of Sciences
  • 22 January 2019
Significance The impact of additional education on later-life cognition remains unclear. After accounting for general cognitive ability (GCA) at age 20 y, education, occupational complexity, orExpand
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Neural correlates of metacognitive monitoring during episodic and semantic retrieval
Activity in the posterior parietal cortex (PPC) has been shown to be a strong correlate of successful recognition performance. We assessed the degree to which the PPC mediates metacognitive judgmentsExpand
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Task-evoked pupil dilation and BOLD variance as indicators of locus coeruleus dysfunction
Pupillary responses during cognitive tasks are linked to functioning of the locus coeruleus (LC). The LC is an early site of abnormal tau deposition, which may contribute to key aspects ofExpand
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Underdiagnosis of mild cognitive impairment: A consequence of ignoring practice effects
Longitudinal testing is necessary to accurately measure cognitive change. However, repeated testing is susceptible to practice effects, which may obscure true cognitive decline and delay detection ofExpand
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The generation effect: Activating broad neural circuits during memory encoding
The generation effect is a robust memory phenomenon in which actively producing material during encoding acts to improve later memory performance. In a functional magnetic resonance imaging (fMRI)Expand
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Predominantly global genetic influences on individual white matter tract microstructure
&NA; Individual differences in white matter tract microstructure, measured with diffusion tensor imaging (DTI), demonstrate substantial heritability. However, it is unclear to what extent thisExpand
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Genetic and Environmental Influences on Verbal Fluency in Middle Age: A Longitudinal Twin Study
Mounting evidence suggests that measures of phonemic fluency and semantic fluency are differentially associated with other cognitive and health phenotypes, but few studies have examined their sharedExpand
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