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1. Ca2+ liberation induced in Xenopus oocytes by a poorly metabolized derivative of inositol 1,4,5-trisphosphate (3-deoxy-3-fluoro-D-myo-inositol 1,4,5-trisphosphate; 3-F-InsP3) was visualized using a video-rate confocal microscope to image fluorescence signals reported by the indicator dye calcium green-1. 2. Low (10-30 nM) intracellular concentrations of(More)
Liberation of sequestered Ca2+ ions in Xenopus oocytes by the second messenger inositol 1,4,5-trisphosphate (InP3) occurs from functionally discrete sites, which are spaced at intervals of several microns and probably represent clusterings of InsP3 receptor/channels (InsP3R) in the endoplasmic reticulum. As well as requiring InsP3, opening of release(More)
The compressive response of a NiTi shape-memory alloy is investigated at high strain rates, using UCSDÕs modified split Hopkinson pressure bar and a mini-Hopkinson bar with specially designed striker bars. To obtain a constant strain rate during the formation of the stress-induced martensite phase in a Hopkinson test, a copper-tube pulse shaper of suitable(More)
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