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AIMS To find out the pharmacokinetic and pharmacodynamic drug interaction of carbamazepine, a protype drug used to treat painful diabetic neuropathy with glibenclamide in healthy albino Wistar rats following single and multiple dosage treatment. MATERIALS AND METHODS Therapeutic doses (TD) of glibenclamide and TD of carbamazepine were administered to the(More)
Effect of epidural steroid injection has been studied in 107 cases (50 males and 57 females, mostly above 20 years of age) with non-specific low backache. Out of 42 cases with acute syndrome 20(47.6%) showed good response, 10(23.8%) showed fair response and 12(28.6%) showed poor response, whereas similar responses were found in 5(7.7%), 10(15.4%) and(More)
A high performance liquid chromatographic (HPLC) method for the simultaneous determination of phenytoin (CAS 57-41-0), phenobarbital (CAS 50-06-6, phenobarbitone) and carbamazepine (CAS 298-46-4) is described. The serum was extracted with ethyl acetate, the dried extract was reconstituted in mobile phase and the aliquot was injected. The eluent drugs were(More)
The existence of stochastic resonance has been demonstrated in physical, biological and geological systems for boosting weak signals to make them detectable. Narrow regions, small features and low-contrast or subtle edges, in noisy images, correspond to such weak signals. In this paper, the occurrence and exploitation of stochastic resonance in the(More)
The study was undertaken to identify an isoelastic graft material for the anterior cruciate ligament (ACL). Double transducer ultrasonic pulse transmission method was employed for determining the elastic properties of normal ACL in comparison with various graft materials like the central third of the patellar tendon, semitendinosus and iliotibial band in(More)
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