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We have hypothesized that a major role of the apical H(+)-pump in mitochondria-rich (MR) cells of amphibian skin is to energize active uptake of Cl- via an apical Cl-/HCO3(-)-exchanger. The activity of the H+ pump was studied by monitoring mucosal [H+]-profiles with a pH-sensitive microelectrode. With gluconate as mucosal anion, pH adjacent to the cornified(More)
A mathematical model of an absorbing leaky epithelium is developed for analysis of solute coupled water transport. The non-charged driving solute diffuses into cells and is pumped from cells into the lateral intercellular space (lis). All membranes contain water channels with the solute passing those of tight junction and interspace basement membrane by(More)
AIM By mathematical modelling, we analyse conditions for near-isotonic and isotonic transport by mammalian kidney proximal tubule. METHODS The model comprises compliant lateral intercellular space (lis) and cells, and infinitely large luminal and peritubular compartments with diffusible species: Na+, K+, Cl- and an intracellular non-diffusible anion.(More)
The actuator line technique was introduced as a numerical tool to be employed in combination with large eddy simulations to enable the study of wakes and wake interaction in wind farms. The technique is today largely used for studying basic features of wakes as well as for making performance predictions of wind farms. In this paper, we give a short(More)
We propose algorithms for developing (1) a rigid (constrained) and (2) a exible planetary gearbox model. The two methods are compared against each other and advantages/disadvantages of each method are discussed. The rigid model (1) has gear tooth reaction forces expressed by Lagrange multipliers. The exible approach (2) is being compared with the gear tooth(More)
abstract We have hypothesized that a major role of the apical H ϩ-pump in mitochondria-rich (MR) cells of amphibian skin is to energize active uptake of Cl Ϫ via an apical Cl Ϫ /HCO 3 Ϫ-exchanger. The activity of the H ϩ pump was studied by monitoring mucosal [H ϩ ]-profiles with a pH-sensitive microelectrode. With gluconate as mu-cosal anion, pH adjacent(More)
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