Jenny Shrestha

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Involvement of the human immunodeficiency virus type 1 (HIV-1) trans-activator of transcription (Tat) protein in neuronal deregulation and in the development of HIV-1 associated neurocognitive disorders (HAND) has been amply explored; however the mechanisms involved remain unclear. In search for the mechanisms, we demonstrated that Tat deregulates neuronal(More)
Background It is estimated that by 2015, about half of all HIV-positive individuals will be older than 50 due to the introduction of the HAART. Yet those over 50 progress to AIDS faster than adults in their 20s or 30s, and those in the younger age bracket still exhibit illnesses and clinical conditions commonly associated with older people, such as(More)
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