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BACKGROUND Malignant mesothelioma reportedly shows different epidemiology and pathology in females, and a proportion are believed to arise spontaneously. METHODS One hundred and seventy seven cases of malignant mesothelioma in females were reviewed, examined by histochemistry and immunohistochemistry, assessed for asbestosis and lung fibre burden by(More)
The cross-sectional area of diaphragmatic muscle fibres was measured using a Quantimet 720 image analysis system in 18 patients with emphysema and six control non-emphysematous patients. The technique proved to be an accurate method of measuring muscle fibre area and much more rapid than the previously described methods. The mean cross-sectional area of the(More)
Circadian behavioral rhythms in mammals are controlled by a central clock located in the suprachiasmatic nucleus (SCN). PER2, the protein product of the clock gene, Period 2 (Per2), is expressed rhythmically in the SCN [Beaule C, Houle LM, Amir S (2003) Expression profiles of PER2 immunoreactivity within the shell and core regions of the rat suprachiasmatic(More)
This study compared the perinatal and obstetric outcomes of 1552 donor insemination pregnancies in Victoria, Australia, with a control group of 7717 normally conceived pregnancies from the general population. Data on the outcomes of pregnancies of at least 20 weeks gestation, for both groups, were obtained from the same population-based birth registry. The(More)
Digitalis is now in common use following acute myocardial infarction, and the danger of producing arrhythmias appears to be no greater than in other groups of patients (Askey, 1951). The drug is frequently given intravenously for a rapid effect and to ensure that it will enter the circulation, but little is known of the immediate effects of such(More)
There is now considerable evidence that the N-methyl-D-aspartic acid receptor is important in the genesis of seizures. One of the selective antagonist of the NMDA receptor is 2-amino-7-phosphonoheptanoic acid (APH). In this study we evaluated the effects of intracerebroventricular (i.c.v.) administration of APH on seizure susceptibility in both prepubescent(More)
Racemic propranolol has been shown to be an effective antidysrhythmic agent in many circumstances (Frieden, 1967; Gettes and Surawicz, 1967; Gibson and Sowton, 1969), including the management of ventricular fibrillation following infarction (Sloman, Robinson, and McLean, 1965). Its depressant effects on myocardial function (Bay, Lund-Larsen, Lorentsen, and(More)
Norwalk virus infection was sought in 48 US, 49 Puerto Rican, and 27 Mexican adults attending medical school in Guadalajara (Mexico) who were enrolled in a 2-year longitudinal study. Serum specimens were collected quarterly and as acute- and convalescent-phase samples around episodes of gastroenteritis. The reciprocal Norwalk virus geometric mean titer(More)
BACKGROUND Since 2005, Australian clinicians were advised to undertake quarterly syphilis testing for all sexually active HIV-positive men who have sex with men (MSM). We describe differences in syphilis testing frequency among HIV-positive MSM by clinic testing policies since this recommendation. METHODS Three general practices, two sexual health clinics(More)