Jennine M Michaud

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The INK4a proteins p16(INK4a) and p19(ARF) regulate cell cycle arrest and senescence. However, the role of these proteins in controlling these processes in the normal kidney and following injury is unknown. We performed unilateral ureteral obstruction (UUO) to induce fibrosis in 2- to 3-mo-old wild-type (WT) C57/B6 and INK4a knockout mice. By quantitative(More)
In a cohort of 23 critically ill patients receiving continuous renal replacement therapy, we investigated the role of ultrafiltrate fluid cultures as an adjunct to blood cultures in identifying the microbial etiology of sepsis. We found they provided no additional benefit and may yield false positives due to contamination.
[PDF] [Full Text] [Abstract] , February , 2010; 298 (2): F365-F380. Am J Physiol Renal Physiol Nesbit, Patrik Rorsman, Olivier Devuyst, Frances M. Ashcroft and Rajesh V. Thakker Galvanovskis, Siân E. Williams, Francois Jouret, Fiona T. F. Wu, Pierre J. Courtoy, M. Andrew Anita A. C. Reed, Nellie Y. Loh, Sara Terryn, Jonathan D. Lippiat, Chris Partridge,(More)
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