Jennifer V. Hines

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The T box transcription antitermination regulatory system, found in Gram-positive bacteria, is dependent on a complex set of interactions between uncharged tRNA and the 5'-untranslated mRNA leader region of the regulated gene. One of these interactions involves the base pairing of the acceptor end of cognate tRNA with four bases in a 7 nt bulge of the(More)
The T box riboswitch controls bacterial transcription by structurally responding to tRNA aminoacylation charging ratios. Knowledge of the thermodynamic stability difference between two competing structural elements within the riboswitch, the terminator and the antiterminator, is critical for effective T box-targeted drug discovery. The ΔG of aminoacyl tRNA(More)
The intramolecular dipolar cycloaddition of an azide with an alkyne has provided a useful entry into triazole fused tricyclic heterocycles containing both the triazole ring and the oxazolidin-2-one ring system. The requisite azido-alkynes have been prepared via a two-step sequence from fused ring aziridines. A series of 6-12 membered rings containing both(More)
  • Vibert C Cambridge, Ohio U, +153 authors Frank E Bernard
  • 2005
The following listings were submitted by the dean's office in each college in May 2005 and collated in the provost's office. The regional campus faculties are listed after the Athens campus faculty. While care is taken to render the data in this list accurately, we regret that mistakes sometimes occur, given the volume of information contained within.(More)
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