Jennifer Seifert

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CONTEXT Cod liver oil supplements in infancy have been associated with a decreased risk of type 1 diabetes mellitus in a retrospective study. OBJECTIVE To examine whether intakes of omega-3 and omega-6 fatty acids are associated with the development of islet autoimmunity (IA) in children. DESIGN, SETTING, AND PARTICIPANTS A longitudinal, observational(More)
The involvement of different regions of the brain in the immune response was investigated with the aid of small electrolytic lesions. The lesions were placed in such a way that they covered different areas of the brain stem, basal ganglia, but also some parts of the frontal cortex. The cellular immune response as well as DNA synthesis with the aid of(More)
BACKGROUND Infant dietary exposures have been linked to type 1 diabetes (T1D) development. IgG4 antibody responses to food antigens are associated with food intolerances but have not been explored prospectively in the period preceding T1D. METHODS Using a case-cohort design, IgG4 antibodies to ß-lactoglobulin, gluten, and ovalbumin were measured in plasma(More)
BACKGROUND Timing of solid food introduction in infancy has been associated with several chronic diseases. To explore potential mechanisms, we investigated the relationship between timing of solid food introduction and F2-isoprostanes-a marker of oxidative stress. METHODS Urinary F2-isoprostanes were assessed in 336 healthy children aged less than 11.5 y(More)
On the basis of our previous investigations concerning the influence of some central nervous system structures on the immune reaction, we have shown the existence of a brain regulatory system for immune response (BRSIR). We have investigated this BRSIR using small electrolytic lesions placed in different brain areas of male rats, followed by two methods to(More)
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