Jennifer Moodie

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BACKGROUND We previously described a composite MRI scale combining T1-lesions, T2-lesions and whole brain atrophy in multiple sclerosis (MS): the magnetic resonance disease severity scale (MRDSS). OBJECTIVE Test strength of the MRDSS vs. individual MRI measures for sensitivity to longitudinal change. METHODS We studied 84 MS patients over a 3.2±0.3 year(More)
BACKGROUND Although cigarette smokers are at increased risk of developing multiple sclerosis (MS), the effect of smoking on the progression of MS remains uncertain. OBJECTIVE To establish the relationship between cigarette smoking and progression of MS using clinical and magnetic resonance imaging outcomes DESIGN Cross-sectional survey and longitudinal(More)
Of 81 adult patients with community-acquired pneumonia, bacterial infections were found in 37%, mycoplasma and viral infections in 21%, and tuberculosis in 6%; no pathogen could be identified in 46% of cases. More than one agent was identified in 12% of patients. Streptococcus pneumoniae, the most common pathogen, was found in 63%, Haemophilus influenzae in(More)
This preliminary study indicates that a high proportion of adult females in Cape Town are immune to rubella, and that, unlike the situation in the UK, natural rubella infections are common before 4 years of age. At least 10 children with the congenital rubella syndrome have been seen in the Cape Town group of teaching hospitals in a 5 1/2-year period since(More)
Multiple sclerosis (MS) is a disease of the central nervous system with both an inflammatory and degenerative component. The disease primarily affects young adults and results in significant physical and cognitive disability. Several disease-modifying agents are currently used in the management of multiple sclerosis. Glatiramer acetate (GA, Copaxone,(More)
The distribution of the morphological types of Australia antigen in 50 blood donors and two patients with serum hepatitis is described.The significance of the high incidence of immune complexes and Dane particles in these persistent carriers is discussed.
Negative staining electron microscopy was used to examine culture fluids from the H9/HTLV-III cell line after concentration by centrifugation. Characteristic retrovirus-like particles bearing distinctive envelope projections were seen. The virion envelope was frequently extended in the form of a bleb or a tail. These particles were morphologically virtually(More)