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Definition of a FoxA 1 Cistrome That Is Crucial for G 1 to S-Phase Cell-Cycle Transit in Castration-Resistant Prostate Cancer
The enhancer pioneer transcription factor FoxA1 is a global mediator of steroid receptor (SR) action in hormone-dependent cancers. In castration-resistant prostate cancer (CRPC), FoxA1 acts as anExpand
  • 5
  • Open Access
Transcription and mRNA Stability Castration-Resistant Prostate Cancer via Attenuation of UBE 2 C M Progression and Invasion of − CCI-779 Inhibits Cell-Cycle G 2
The cell-cycle G2–Mphase gene UBE2C is overexpressed in various solid tumors including castration-resistant prostate cancer (CRPC). Our recent studies found UBE2C to be a CRPC-specific androgenExpand
  • 1
  • Open Access