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The authors hypothesized that teasing, a social interaction that benefits relational bonds at the expense of the self, should be viewed as more affiliative, and experienced as more pleasurable, by members of cultures that deemphasize positive self-differentiation. In four multimethod studies, Asian Americans attributed more affiliative intent to teasers and(More)
The aim of this study was to assess diaphragm electrical activation and diaphragm strength in patients with advanced Duchenne muscular dystrophy during resting conditions. Eight patients with advanced Duchenne muscular dystrophy (age of 25 +/- 2 years) were studied during tidal breathing, maximal inspiratory capacity, maximal sniff inhalations, and magnetic(More)
The first author can be reached by phone at (413)577-4271; the second can be reached at (631)632-7840. We would like to thank Glenda Villareal for her help with stimulus construction, and three anonymous reviewers for their helpful comments on this manuscript. *My position at IIT begins 8/04. Until then I can be reached at the University of Massachusetts;(More)
OBJECTIVE Patient-ventilator synchrony during non-invasive pressure support ventilation with the helmet device is often compromised when conventional pneumatic triggering and cycling-off were used. A possible solution to this shortcoming is to replace the pneumatic triggering with neural triggering and cycling-off-using the diaphragm electrical activity(More)
INTRODUCTION The aim of this study was to validate an automated, objective and standardized algorithm for quantifying and displaying patient-ventilator interaction. METHODS Using a new method to detect patient-ventilator synchrony, the present study re-analyzed previously acquired and published data from 24 mechanically ventilated adult patients (Colombo(More)
INTRODUCTION Based on the hypothesis that failure of weaning from mechanical ventilation is caused by respiratory demand exceeding the capacity of the respiratory muscles, we evaluated whether extubation failure could be characterized by increased respiratory drive and impaired efficiency to generate inspiratory pressure and ventilation. METHODS Airway(More)
OBJECTIVES Reduction of breathing variability is associated with adverse outcome. During mechanical ventilation, the variability of ventilatory pressure is dependent on the ventilatory mode. During neurally adjusted ventilatory assist (NAVA), the support is proportional to electrical activity of the diaphragm (EAdi), which reflects the respiratory center(More)
This study evaluated the response to increasing levels of neurally adjusted ventilatory assist (NAVA), a mode converting electrical activity of the diaphragm (EAdi) into pressure, regulated by a proportionality constant called the NAVA level. Fourteen rabbits were studied during baseline, resistive loading and ramp increases of the NAVA level. EAdi, airway(More)
Binding of the mGlu2/3 antagonist HYDIA in the closed conformation model of mGlu2 causes repulsive interactions with Y216 in lobe II of the binding pocket, preventing closure of the VFT.Modulation of metabotropic glutamate 2/3 receptors represents a promising target for the treatment of neuropsychiatric disorders such as schizophrenia and depression. The(More)