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The corticobulbar projection to musculotopically defined subsectors of the facial nucleus was studied from the face representation of the primary (M1), supplementary (M2), rostral cingulate (M3), caudal cingulate (M4) and ventral lateral pre- (LPMCv) motor cortices in the rhesus monkey. We also investigated the corticofacial projection from the face/arm(More)
Localization of the corticofugal projection in the corona radiata (CR) and internal capsule (IC) can assist in evaluating a patient's residual motor capacity following subtotal brain damage and predicting their potential for functional restitution. To advance our understanding of the organization of the corticofugal projection in this critical brain region,(More)
© 2 0 0 3 m a s s a c h u s e t t s i n s t i t u t e o f t e c h n o l o g y, c a m b r i d g e , m a 0 2 1 3 9 u s a — w w w. a i. m i t. e d u Abstract Previous biological models of object recognition in cortex have been evaluated using idealized scenes and have hard-coded features, such as the HMAX model by Riesenhuber and Poggio [10]. Because HMAX uses(More)
The corticospinal projection from the cingulate motor cortex to the lower cervical enlargement (C5-T1) was investigated in four rhesus monkeys. Each received an injection of biotinylated dextran amine involving the arm representation of M3 (area 24c) or M4 (area 23c). In M3 cases, contralateral terminal label occurred in the lateral part of laminae V and VI(More)
Models of object recognition in cortex have so far been mostly applied to tasks involving the recognition of isolated objects presented on blank backgrounds. However, ultimately models of the visual system have to prove themselves in real world object recognition tasks. Here we took a first step in this direction: We investigated the performance of the hmax(More)
Automatic indexing of large collections of multimedia data is important for enabling retrieval functions. Current approaches mostly draw on a single or dual modality of video content analysis. Here we describe a framework for the integration of multimedia content and context information, which generalizes and systematizes current methods. Content(More)
BACKGROUND Pembrolizumab is a monoclonal antibody that is designed against programmed cell death protein 1 (PD-1). Pembrolizumab and other immunocheckpoint-blocking monoclonal antibodies work by modulating a patient's own immune system to increase anti-tumor activity. While immunocheckpoint blockade has shown promising results, only 20-40 % of patients(More)
Previous biological models of object recognition in cortex have been evaluated using idealized scenes and have hard-coded features, such as the HMAX model by Riesen-huber and Poggio [10]. Because HMAX uses the same set of features for all object classes, it does not perform well in the task of detecting a target object in clutter. This thesis presents a new(More)
The Problem: To evaluate a biological model of object recognition that uses feature learning to distinguish between classes of objects. Motivation: On the computational neuroscience side, applying a biologically plausible model of object recognition to a real world task, namely face detection, tests out whether the concepts behind the model hold. Current(More)