Menstrual irregularity is a common occurrence during adolescence, especially within the first 2-3 years after menarche. Prolonged amenorrhea, however, is not normal and can be associated with significant medical morbidity, which differs depending on whether the adolescent is estrogen-deficient or estrogen-replete. Estrogen-deficient amenorrhea is associated… (More)
PURPOSE To determine the effect of dimethylfumarate (DMF), an inducer of glutathione (GSH)-dependent detoxification, on intracellular GSH levels in cultured human retinal pigment epithelium (hRPE) cells, its mechanism of action, and its effect on hRPE cells subjected to oxidative injury. METHODS Established hRPE cell lines were treated with DMF and… (More)
This case study describes how Cisco followed a "Rapid Experimentation" methodology in conducting iterative, high velocity pilot studies to inform a large global customer service experience design project. The research findings described in this case study informed the design of a better mechanism for customers to select their expected outcomes, so Cisco can… (More)
What are the requirements for a mobile app to be successful in multiple languages? Cisco Systems developed a mobile application, SalesConnect, for its internal sales force of tens of thousands, as well as partners across the globe. Before investing in costly localization, the team wanted to learn: What is most important to sales users for a localized app?… (More)
This paper describes an experience study to understand the user perceptions on two camera focus settings in a TelePresence room: limited-and infinite-Depth-of-Field. The results influence future TelePresence experience design.