Jennifer J. Kurinczuk

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BACKGROUND It is not known whether infants conceived with use of intracytoplasmic sperm injection or in vitro fertilization have a higher risk of birth defects than infants conceived naturally. METHODS We obtained data from three registries in Western Australia on births, births after assisted conception, and major birth defects in infants born between(More)
BACKGROUND The risk of birth defects in infants born following assisted reproductive technology (ART) treatment is a controversial question. Most publications examining the prevalence of birth defects in ICSI and IVF infants compared to spontaneously conceived infants have serious methodological limitations; despite this, most researchers have concluded(More)
Neonatal encephalopathy (NE) is the clinical manifestation of disordered neonatal brain function. Lack of universal agreed definitions of NE and the sub-group with hypoxic-ischaemia (HIE) makes the estimation of incidence and the identification of risk factors problematic. NE incidence is estimated as 3.0 per 1000 live births (95%CI 2.7 to 3.3) and for HIE(More)
OBJECTIVE To ascertain antepartum predictors of newborn encephalopathy in term infants. DESIGN Population based, unmatched case-control study. SETTING Metropolitan area of Western Australia, June 1993 to September 1995. SUBJECTS All 164 term infants with moderate or severe newborn encephalopathy; 400 randomly selected controls. MAIN OUTCOME MEASURES(More)
OBJECTIVE To investigate the burden of later disease associated with moderate/late preterm (32-36 weeks) and early term (37-38 weeks) birth. DESIGN Secondary analysis of data from the Millennium Cohort Study (MCS). SETTING Longitudinal study of infants born in the United Kingdom between 2000 and 2002. PARTICIPANTS 18,818 infants participated in the(More)
OBJECTIVE To estimate the national incidence of peripartum hysterectomy and quantify the risk associated with cesarean deliveries and other factors. METHODS A population-based, matched case-control study using the United Kingdom Obstetric Surveillance System, including 318 women in the United Kingdom who underwent peripartum hysterectomy between February(More)
OBJECTIVE To identify intrapartum predictors of newborn encephalopathy in term infants. DESIGN Population based, unmatched case-control study. SETTING Metropolitan area of Western Australia, June 1993 to September 1995. SUBJECTS All 164 term infants with moderate or severe newborn encephalopathy; 400 randomly selected controls. MAIN OUTCOME MEASURES(More)
OBJECTIVE To test the hypothesis that liveborn infants conceived by intracytoplasmic sperm injection are at an increased risk of having a major birth defect. DESIGN Reclassification of the birth defects reported in infants born after intracytoplasmic sperm injection in Belgium and comparison with prevalence estimated in Western Australian population by(More)
Cerebral palsy (CP) can occur in term infants with or without preceding newborn encephalopathy. We compared the type and severity of CP and associated disability in these two groups. Participants from a population-based case-control study of term newborn encephalopathy were followed up for 6 years and linked to the Western Australian Cerebral Palsy(More)
OBJECTIVES To follow up a UK national cohort of women admitted to hospital with confirmed 2009/H1N1 influenza in pregnancy in order to obtain a complete picture of pregnancy outcomes and estimate the risks of adverse fetal and infant outcomes. DESIGN National cohort study. SETTING 221 hospitals with obstetrician led maternity units in the UK. (More)